全文获取类型
收费全文 | 3757篇 |
免费 | 244篇 |
国内免费 | 63篇 |
专业分类
耳鼻咽喉 | 7篇 |
儿科学 | 181篇 |
妇产科学 | 57篇 |
基础医学 | 584篇 |
口腔科学 | 54篇 |
临床医学 | 263篇 |
内科学 | 367篇 |
皮肤病学 | 17篇 |
神经病学 | 56篇 |
特种医学 | 41篇 |
外科学 | 84篇 |
综合类 | 453篇 |
一般理论 | 1篇 |
预防医学 | 1490篇 |
眼科学 | 10篇 |
药学 | 259篇 |
2篇 | |
中国医学 | 68篇 |
肿瘤学 | 70篇 |
出版年
2023年 | 63篇 |
2022年 | 100篇 |
2021年 | 142篇 |
2020年 | 142篇 |
2019年 | 156篇 |
2018年 | 133篇 |
2017年 | 106篇 |
2016年 | 124篇 |
2015年 | 137篇 |
2014年 | 255篇 |
2013年 | 247篇 |
2012年 | 241篇 |
2011年 | 229篇 |
2010年 | 187篇 |
2009年 | 191篇 |
2008年 | 145篇 |
2007年 | 163篇 |
2006年 | 130篇 |
2005年 | 129篇 |
2004年 | 137篇 |
2003年 | 111篇 |
2002年 | 102篇 |
2001年 | 103篇 |
2000年 | 75篇 |
1999年 | 64篇 |
1998年 | 54篇 |
1997年 | 35篇 |
1996年 | 32篇 |
1995年 | 47篇 |
1994年 | 35篇 |
1993年 | 30篇 |
1992年 | 30篇 |
1991年 | 24篇 |
1990年 | 17篇 |
1989年 | 25篇 |
1988年 | 11篇 |
1987年 | 15篇 |
1986年 | 11篇 |
1985年 | 23篇 |
1984年 | 18篇 |
1983年 | 5篇 |
1982年 | 11篇 |
1981年 | 5篇 |
1980年 | 4篇 |
1979年 | 4篇 |
1978年 | 6篇 |
1977年 | 4篇 |
1976年 | 3篇 |
1970年 | 1篇 |
1968年 | 1篇 |
排序方式: 共有4064条查询结果,搜索用时 15 毫秒
1.
《Vaccine》2022,40(52):7604-7612
Background and ObjectiveVaccine uptake during pregnancy remains low. Our objectives were to describe 1) development and adaptation of a clinician communication training intervention for maternal immunizations and 2) obstetrics and gynecology (ob-gyn) clinician and staff perspectives on the intervention and fit for the prenatal care context.MethodsDesign of the Motivational Interviewing for Maternal Immunizations (MI4MI) intervention was based on similar communication training interventions for pediatric settings and included presumptive initiation of vaccine recommendations (“You’re due for two vaccines today”) combined with motivational interviewing (MI) for hesitant patients. Interviews and focus group discussions were conducted with ob-gyn clinicians and staff in five Colorado clinics including settings with obstetric physicians, certified nurse midwives (CNMs), and clinician-trainees. Participants were asked about adapting training to the ob-gyn setting and their implementation experiences. Feedback was incorporated through iterative changes to training components.ResultsInterview and focus group discussion results from participants before (n = 3), during (n = 11) and after (n = 25) implementation guided intervention development and adaptation. Three virtual, asynchronous training components were created: a video and two interactive modules. This virtual format was favored due to challenges attending group meetings; however, participants noted opportunities to practice skills through role-play were lacking. Training modules were adapted to include common challenging vaccine conversations and live-action videos. Participants liked interactive training components and use of adult learning strategies. Some participants initially resisted the presumptive approach but later found it useful after applying it in their practices. Overall, participants reported that MI4MI training fit well with the prenatal context and recommended more inclusion of non-clinician staff.ConclusionsMI4MI training was viewed as relevant and useful for ob-gyn clinicians and staff. Suggestions included making training more interactive, and including more complex scenarios and non-clinician staff. 相似文献
2.
《Vaccine》2022,40(18):2525-2527
3.
《Vaccine》2022,40(44):6431-6444
This is a Brighton Collaboration case definition of thrombosis and thromboembolism to be used in the evaluation of adverse events following immunization, and for epidemiologic studies for the assessment of background incidence or hypothesis testing. The case definition was developed by a group of experts convened by the Coalition for Epidemic Preparedness Innovations (CEPI) in the context of active development of SARS-CoV-2 vaccines. The case definition format of the Brighton Collaboration was followed to develop a consensus definition and defined levels of certainty, after an exhaustive review of the literature and expert consultation. The document underwent peer review by the Brighton Collaboration Network and by selected expert reviewers prior to submission. 相似文献
4.
《Vaccine》2022,40(41):5997-6000
Coronavirus disease 2019 (COVID-19) vaccine administration started in February 2021 in Japan. As of December 2021, approximately 75% of the population aged ≥12 years had received two doses of vaccine. We conducted a study to investigate vasovagal reactions (VVR) after COVID-19 vaccination using data on adverse events following immunization. The crude reporting rate of VVR (cases/1,000,000 doses) after vaccination was 9.6 in all age groups combined, and was more frequent in the younger age groups: 28.6 and 37.2 in individuals aged 10–19 years and 20–29 years, respectively. In individuals aged 10–29 years, the rate was similar in males and females (33.0 and 34.2, respectively, p = 0.53); but was higher after dose 1 than after dose 2 (57.4 and 8.8, respectively, p < 0.001). Based on these results, caution needs to be exercised when vaccinating adolescents and young adults, especially with dose 1 of COVID-19 vaccines. 相似文献
5.
《Vaccine》2019,37(24):3190-3198
The development of a group B Streptococcus (GBS) vaccine for maternal immunization constitutes a global public health priority, to prevent GBS-associated early life invasive disease, stillbirth, premature birth, maternal sepsis, adverse neurodevelopmental consequences, and to reduce perinatal antibiotic use. Sample size requirements for the conduct of a randomized placebo-controlled trial to assess vaccine efficacy against the most relevant clinical endpoints, under conditions of appropriate ethical standards of care, constitute a significant obstacle on the pathway to vaccine availability. Alternatively, indirect evidence of protection based on immunologic data from vaccine and sero-epidemiological studies, complemented by data from opsonophagocytic in vitro assays and animal models, could be considered as pivotal data for licensure, with subsequent confirmation of effectiveness against disease outcomes in post-licensure evaluations. Based on discussions initiated by the World Health Organization we present key considerations about the potential role of correlates of protection towards an accelerated pathway for GBS vaccine licensure and wide scale use. Priority activities to support progress to regulatory and policy decision are outlined. 相似文献
6.
Introduction
The Advisory Committee on Immunization Practices (ACIP) has focused on maternal Tdap immunization as an important means to protect neonates from pertussis infections. There is little published data on provider and/or clinic characteristics as predictors of maternal Tdap uptake. This study examined differences in maternal Tdap coverage in women delivering at a single academic institution, but cared for prenatally in different clinical settings, in 2013, 2014, and 2015. Additionally, the accuracy and utilization of Vermont's immunization information system (IIS) was assessed.Methods
This was a retrospective, multiple time-point cross-sectional analysis of annual maternal Tdap coverage in women delivering at a single academic institution in the 3?years following a fundamental change in national maternal Tdap vaccination guidelines. Tdap administration was examined across different obstetric groups using chart review and data from the state's IIS.Results
All obstetric care groups except the resident-staffed clinic significantly increased maternal Tdap coverage in 2014, compared to 2013 coverage, with no further increase in 2015. In contrast, there was no increase in maternal Tdap coverage in 2014 in the resident-staffed clinics, but then a statistically significant increase in 2015. Overall Tdap coverage in 2014 was 80.4%, with variation in Tdap coverage between clinics types. In the subset of women who were cared for by the University-based groups, there was significant variation in Tdap coverage between clinics, despite racial homogeneity, which persisted after adjustment for maternal age and insurance type. The state's IIS was found to be highly accurate, using individual chart review as the “gold standard.”Discussion
While we demonstrated high maternal Tdap coverage in women delivering at our institution, differences in clinic type and provider training appeared to impact immunization rates, as well as how quickly evolving national recommendations were adopted. Additionally, the fidelity of the state's IIS data was verified. 相似文献7.
Bethany Figg 《Journal of consumer health on the Internet》2019,23(1):70-82
The National Vaccine Program Office (NVPO) manages <www.vaccines.gov> and is part of the U.S. Department of Health and Human Services (HHS). Vaccines.gov offers reliable information from the federal government on vaccines, immunizations, and vaccine-preventable diseases. The web site works with the Centers for Disease Control and Prevention (CDC), National Institutes of Health (NIH), Food and Drug Administration (FDA) and many other government agencies to ensure all information on the web site is accurate and relevant. The web site encourages readers to share the information on the site with friends, family, and patients to promote health literacy on vaccines. 相似文献
8.
9.
10.